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This document discusses pharmaceutical suspensions. A suspension is actually a coarse dispersion exactly where an insoluble stable drug is dispersed through a liquid medium. Suspensions are formulated when medication are insoluble, to mask bitter taste, raise steadiness, or allow for controlled drug release. Widespread varieties include things like
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This reactive epoxide intermediate might respond with amino acid residues of the CYP enzyme to form drug-CYP (drug-protein) adducts (Plan 6, pathway C). The formation of the drug-CYP adducts might or might not reveal a time-dependent inactivation of the catalytic activity of this CYP enzyme, dependant upon the covalent binding in the reactive inter